Nanobots Therapeutics
Therapeutics In-Motion
COMPANY
Nanobots Therapeutics is a deeptech company focused on developing and commercializing MotionTx platform.
MotionTx technology enables the development of unique therapeutic entities that penetrate tissues with superior efficacy, enhancing drug accumulation in target cells.
The company is a spin-off of ICREA and IBEC and is the result of the research led by Prof. Samuel Sánchez.
MotionTx technology enables the development of unique therapeutic entities that penetrate tissues with superior efficacy, enhancing drug accumulation in target cells.
The company is a spin-off of ICREA and IBEC and is the result of the research led by Prof. Samuel Sánchez.
SCIENCE
Our science is pioneering the development of MotionTx platform, a new modality of therapeutic entities with unique properties to penetrate tissues and accumulate in target cells. What is MotionTx?
New Modality
Novel class of drugs with unique tissue penetration capabilities
Platform Technology
Can carry a variety of drugs for different therapeutic indications
Targeted Delivery
Maximizing local routes of administration
SCIENTIFIC PUBLICATIONS
Urease-powered nanobots for radionuclide bladder cancer therapy
Simó C, Serra-Casablancas M, Hortelao AC, Di Carlo V, Guallar-Garrido S, Plaza-García S, Rabanal RM, Ramos-Cabrer P, Yagüe B, Aguado L, Bardia L, Tosi S, Gómez-Vallejo V, Martín A, Patiño T, Julián E, Colombelli J, Llop J, Sánchez S.
Nat Nanotechnol. 2024 Jan 15 (online)
Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder
Ana C. Hortelao, Cristina Simó, Maria Guix, Sandra Guallar-Garrido, Esther Julián, Diana Vilela, Luka Rejc, Pedro Ramos-Cabrer, Unai Cossío, Vanessa Gómez-Vallejo, Tania Patiño*, Jordi Llop*, Samuel Sánchez*.
Sci Robot, 2021 Mar 17;6(52)
Enzyme-Powered Gated Mesoporous Silica Nanomotors for On-Command Intracellular Payload Delivery
Antoni Llopis-Lorente, Alba García-Fernández, Nerea Murillo-Cremaes, Ana C. Hortelão, Tania Patiño, Reynaldo Villalonga, Félix Sancenón, Ramón Martínez-Máñez,* and Samuel Sánchez*.
ACS Nano 2019, 13, 12171−12183
Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors
Ana C. Hortelão, Rafael Carrascosa, Nerea Murillo-Cremaes, Tania Patiño,* and Samuel Sánchez*.
ACS Nano 2019, 13, 429−439
Simó C, Serra-Casablancas M, Hortelao AC, Di Carlo V, Guallar-Garrido S, Plaza-García S, Rabanal RM, Ramos-Cabrer P, Yagüe B, Aguado L, Bardia L, Tosi S, Gómez-Vallejo V, Martín A, Patiño T, Julián E, Colombelli J, Llop J, Sánchez S.
Nat Nanotechnol. 2024 Jan 15 (online)
Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder
Ana C. Hortelao, Cristina Simó, Maria Guix, Sandra Guallar-Garrido, Esther Julián, Diana Vilela, Luka Rejc, Pedro Ramos-Cabrer, Unai Cossío, Vanessa Gómez-Vallejo, Tania Patiño*, Jordi Llop*, Samuel Sánchez*.
Sci Robot, 2021 Mar 17;6(52)
Enzyme-Powered Gated Mesoporous Silica Nanomotors for On-Command Intracellular Payload Delivery
Antoni Llopis-Lorente, Alba García-Fernández, Nerea Murillo-Cremaes, Ana C. Hortelão, Tania Patiño, Reynaldo Villalonga, Félix Sancenón, Ramón Martínez-Máñez,* and Samuel Sánchez*.
ACS Nano 2019, 13, 12171−12183
Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors
Ana C. Hortelão, Rafael Carrascosa, Nerea Murillo-Cremaes, Tania Patiño,* and Samuel Sánchez*.
ACS Nano 2019, 13, 429−439
PLATFORM
MotionTx Platform will benefit patients by improving the accumulation of therapeutic drugs in target cells.
NBT-102
Undisclosed indication